Rando Allikmets Selected Research

BPN-14136

1/2018

A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.

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Rando Allikmets Research Topics

Disease

30	Macular Degeneration (Age-Related Maculopathy) 01/2019 - 10/2002
15	Stargardt Disease 01/2018 - 03/2004
9	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2015 - 03/2004
6	Atrophy 01/2022 - 11/2008
5	Retinal Degeneration 01/2022 - 12/2004
4	Disease Progression 10/2020 - 01/2009
3	Retinal Diseases 01/2021 - 08/2009
3	Cone-Rod Dystrophies 11/2013 - 03/2004
2	Retinal Dystrophies 01/2022 - 10/2020
2	Telangiectasis (Telangiectasia) 01/2021 - 10/2019
2	Hypertension (High Blood Pressure) 08/2011 - 12/2010
1	Cystic Fibrosis (Mucoviscidosis) 01/2022
1	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2022
1	Cone Dystrophy 01/2022
1	Fundus Albipunctatus 01/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 10/2019
1	Atypical Hemolytic Uremic Syndrome 01/2018
1	Eye Diseases (Eye Disease) 01/2018
1	Infections 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2018
1	Brachydactyly 04/2017
1	Craniofacial Abnormalities 04/2017
1	Homocystinuria 01/2015
1	Optic Atrophy 01/2015
1	Methylmalonic acidemia 01/2015
1	Rare Diseases (Rare Disease) 11/2014
1	Pre-Eclampsia (Preeclampsia) 07/2014
1	Central Serous Chorioretinopathy 07/2014
1	Enhanced S-Cone Syndrome 10/2013
1	Choroidal Neovascularization 09/2013
1	Geographic Atrophy 09/2013
1	congenital stationary Night blindness 01/2012
1	Polypoidal Choroidal Vasculopathy 06/2011
1	Usher Syndromes (Usher Syndrome) 12/2010
1	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 03/2009
1	Cataract (Cataracts) 01/2009
1	Night Blindness (Nyctalopia) 01/2009
1	Multifocal Choroiditis 11/2008
1	Macular Edema 11/2008

Drug/Important Bio-Agent (IBA)

24	Retinaldehyde (Retinal)IBA 01/2022 - 03/2004
7	LipofuscinIBA 01/2019 - 08/2004
7	Complement Factor H (Factor H)IBA 01/2018 - 05/2005
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2009
4	Retinal Pigments (Pigments, Visual)IBA 07/2014 - 01/2006
3	Serine (L-Serine)FDA Link 01/2021 - 09/2009
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2015 - 08/2004
3	Complement Factor B (Factor B)IBA 07/2011 - 04/2006
3	Complement C2 (Complement Component 2)IBA 07/2011 - 04/2006
2	Melanins (Melanin)IBA 01/2019 - 07/2015
2	ceramide kinaseIBA 01/2019 - 12/2010
2	NucleotidesIBA 01/2018 - 01/2003
2	Adenosine Triphosphate (ATP)IBA 01/2015 - 06/2013
2	ElastinIBA 11/2014 - 06/2011
2	Nonsense Codon (Nonsense Mutation)IBA 11/2014 - 03/2004
2	retinol dehydrogenaseIBA 11/2014 - 12/2010
2	Complement C3 (C3 Complement)IBA 07/2011 - 09/2009
2	Macular PigmentIBA 12/2010 - 10/2002
2	Complement System Proteins (Complement)IBA 03/2010 - 05/2005
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 12/2007 - 12/2004
1	tyrosyltubulin ligaseIBA 01/2022
1	CholesterolIBA 01/2022
1	CeramidesIBA 01/2021
1	Carrier Proteins (Binding Protein)IBA 01/2021
1	retinol dehydrogenase 5IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 10/2020
1	Serine C-PalmitoyltransferaseIBA 10/2019
1	Amino Acids FDA Link 10/2019
1	AntibodiesIBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	RetinoidsIBA 01/2018
1	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2018
1	BPN-14136IBA 01/2018
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 05/2016
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2015
1	Fibrillin-2IBA 11/2014
1	Glycoproteins (Glycoprotein)IBA 11/2014
1	cadherin 5IBA 07/2014
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2014
1	Genetic Markers (Genetic Marker)IBA 09/2013
1	Member 4 Subfamily A ATP Binding Cassette TransporterIBA 01/2012
1	Calcium Channels (Calcium Channel)IBA 01/2012
1	Factor XIII (Coagulation Factor XIII)IBA 07/2011
1	Lipase (Acid Lipase)FDA Link 04/2010
1	Complement C5 (Complement 5)IBA 03/2010
1	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 09/2009
1	Apolipoproteins E (ApoE)IBA 09/2009
1	ApolipoproteinsIBA 09/2009
1	Peptide Hydrolases (Proteases)FDA Link 09/2009
1	DipeptidesIBA 03/2009
1	Arginine (L-Arginine)FDA Link 03/2009
1	Glutamic Acid (Glutamate)FDA Link 03/2009
1	atrophin-1IBA 03/2009
1	Co-Repressor ProteinsIBA 03/2009
1	Fluorescein (Funduscein)FDA LinkGeneric 01/2009
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2009
1	Type 6 Cyclic Nucleotide PhosphodiesterasesIBA 11/2008

Therapy/Procedure

3	Lasers (Laser) 07/2014 - 10/2002
2	Therapeutics 07/2017 - 12/2004
2	Transplantation 10/2010 - 04/2010
1	Length of Stay 07/2014